The clinical decision support systems (CDSS) industry is expected to reach $16.6 billion by the end of 2030 at a compound annual growth rate of 7.6%. Industry initiatives for centralized data platforms and data sharing would support CDSS solutions that can comprehensively understand the multimodal data from these platforms and then share personalized insights. The use of GenAI to power search operations is becoming a base requirement rather than a competitive factor. The focus of using GenAI is now on enhancing user experience, data analytics, and personalization capabilities. In addition, vendors are developing a more proactive CDSS solution (prompt-based) instead of the current reactive systems (physician search). Ambient documentation technology is enabling this shift.  This Frost Radar benchmarks 10 companies that represent the best mix of CDSS-native companies (evidence generation) and companies that can drive visionary innovation at the point of care. A future CDSS platform will combine CDSS output with patient journey and support adjacent administrative and financial workflows enabling vendors to expand the breadth of their offering, enhance the use of their platform, and reduce vendor load for end users. To accelerate this shift and fast-track product development and market entry, partnerships and M&A will play a dominant role.

• Which solutions are primarily sold as a subset of the CDSS with a focus on operational efficiency rather than clinical efficiency, and how will they impact future growth potential?
• Which growth prospects will impact IT platforms capable of supporting providers’ clinical decision-making and customized based on end-user requirements?
• What growth opportunities are emerging for electronic health record and clinical surveillance suppliers?